Thomas Seyfried

Seyfried Argues Mitochondrial Dysfunction, Not Mutations, Starts Cancer

Boston College biologist Thomas Seyfried argues that cancer begins primarily with chronic mitochondrial damage, which pushes cells toward glucose- and glutamine-dependent fermentation; in his account, many genetic mutations are downstream effects rather than the initiating cause. He says that model supports using nutritional ketosis and other metabolic measures alongside chemotherapy, radiation and immunotherapy to pressure tumours’ fuel supply. The source notes that this remains a contested minority view, and that such approaches are experimental rather than established cancer treatment.