Lifestyle Choices May Shape Alzheimer’s Risk Long Before Memory Fails
Neurologist David Perlmutter argues that Alzheimer’s risk is shaped not only by age and inherited susceptibility but also by metabolic and lifestyle conditions that accumulate over time. He links high blood sugar, inflammation, poor sleep, inactivity and social isolation to changes in the brain’s immune cells, and says prevention should begin before memory problems appear. His case is for treating brain health as a long-term concern, not waiting for symptoms or a future treatment.
The Diary of a CEO·Nov 12, 2026·20 min read